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For example, homocysteine (Hcy), an amino acid involved in DNA methylation, facilitates GPX4 methylation that leads to upregulation of oxidative stress and ferroptosis in nucleus pulposus (Zhang et al., 2020c)

[DOI] [PubMed] [Google Scholar] 20.Loke YK, Derry S, Pritchard-Copley A

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A recent study has demonstrated that the inhibition of Nrf2 signalling could significantly promote the incidence of type I diabetes mellitus, and, on the other hand, its reactivation reduces oxidative stress in pancreatic -cells [143]

Chromatographic Separation: A reverse-phase C18 column with a gradient elution profile was used to separate GSH and GSSG from other metabolites

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